There are four primary hormones produced by the HPA Axis, which all work together: When your body produces stress hormones for too long, you can become desensitized to those hormones, which makes homeostasis difficult to maintain.
HPA Axis dysfunction typically begins to happen after periods of chronic stress. Each part of the axis affects the function of the others, so when one part begins to dysfunction, the remaining two parts will begin to suffer as well. The HPA Axis affects a great number of bodily functions including immunity, metabolism, mood, stress response, motivation, and energy levels. Each adrenal sits atop one of your kidneys.
Adrenal Glands– Your adrenal glands produce the stress hormones adrenaline and cortisol. It regulates the other endocrine gland (including the thyroid…the pituitary produces TSH, which in turn makes your thyroid gland function). Pituitary Gland– Often referred to as the Master Gland, the pea-sized pituitary sits at the base of your brain. The hypothalamus regulates sleep, hunger and thirst, emotions, body temperature, and more or in other words, it allows you to maintain homeostasis. It allows your autonomic nervous system to work with your endocrine system and with your pituitary gland. Hypothalamus– The hypothalamus is a section of your forebrain. HPA stands for hypothalamic-pituitary-adrenal, which includes: Today let’s take a look at the function of the HPA Axis and what happens when it begins to function improperly. 
The HPA Axis is something of a buzzword in health and wellness circles.
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